Cataracts in childhood leukaemia.

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Cataracts in childhood leukaemia.

The incidence and severity of cataract were studied in 37 children who had completed treatment for acute lymphoblastic leukaemia. Twelve (32%) had posterior subcapsular lens opacities. Treatment had included corticosteroids and cranial irradiation, but no dose relationship was evident. The boys were more severely affected than the girls. Although none of the lens opacities was optically signifi...

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Hematologic biomarkers in childhood cataracts

PURPOSE To date, more than thirty nine genetic loci have been associated with congenital cataracts. Despite this progress, current diagnostic techniques are insufficient for unraveling the underlying genetic defect in sporadic patients and small families. In the present manuscript we demonstrate the contribution of routine laboratory tests in the search for genetic defects of childhood cataract...

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Monocytic leukaemia in childhood.

In 1913 Reschad and Schilling Torgau suggested the possibility of a distinctive hyperplasia affecting the monocytic cells of the blood under the name of ' splenocytic leukaemia.' With the more accurate title of ' monocytic leukaemia,' this is now an established entity. Though still regarded as a rare disease, this condition is being increasingly recognized. In 1933 only twenty histologically au...

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Development of CNS leukaemia in acute myeloid leukaemia in childhood.

In 130 cases of acute myeloid leukaemia in children below the age of 14 years in Great Britain, there were 21 cases in which the central nervous system was involved. The incidence and timing is similar to that of acute lymphoblastic leukaemia; in a small number of patients who received prophylactic treatment, involvement of the central nervous system was prevented.

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Incidence and Pattern of Childhood Leukaemia in Basrah, Iraq during 2003-2007

Background: Environment of Basrah is seriously contaminated with chemical leukomogens as a result of recent military conflicts. Many studies in the past few years have reported an increase in the incidence of leukemia in Basrah. This study was designed to study the risk and pattern of childhood leukemia in Basrah, Iraq, from 2003 to 2007.Materials and Methods: This hospital-based cancer registr...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1985

ISSN: 0007-1161

DOI: 10.1136/bjo.69.6.459